This is my fav genre of web game, but a lot of them suck, with random illogical clues
This guy Afro-Ninja seems to have mastered them, you beat them by thinking rather than random clicking
He's done a few, here are my faves:
http://www.afro-ninja.com/game/62 (ESCAPE HYPOTHERMIA, you have to beat it in a few minutes)
http://www.afro-ninja.com/game/56 (ESCAPE THE BATHROOM, very nice set of puzzles)
http://www.afro-ninja.com/game/43 (ESCAPE THE CLOSET, quite a quick one)
http://www.afro-ninja.com/game/41 (ESCAPE THE CAR)
http://www.addictinggames.com/escapethephonebooth.html (ESCAPE THE PHONEBOOTH)
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